Online Submission!

Open Journal Systems


G. Delucta Mary


Measurements of retinal blood vessel morphology have been shown to be related to the risk of cardiovascular diseases. The wrong identification of vessels may result in a large variation of these measurements, leading to a wrong clinical diagnosis Both the arteries and veins of the retina are generally binary trees, whose properties can be considered either locally or globally. Measurable geometrical changes in diameter, branching angle, length, or tortuosity, as a result of disease, have been described in retinal blood vessels. The detection and measurement of retinal blood vessels can be used to quantify the severity of disease such as hypertension, stroke and arteriosclerosis, as part of the process of automated diagnosis of disease or in the assessment of the progression of therapy. Thus, a reliable method of vessel detection and quantification would be valuable. In this paper, we address the problem of identifying true vessels as a postprocessing step to vascular structure segmentation. We model the segmented vascular structure as a vessel segment graph and formulate the problem of identifying vessels as one of finding the optimal forest in the graph given a set of constraints.

Full Text:



T.Y.Wong, F. M. A. Islam,R.Klein,B. E.K.Klein,M. F.Cotch,C.Castro,A. R. Sharrett, and E. Shahar, “Retinal vascular caliber, cardiovascular risk factors, and inflammation: The multi-ethnic study of atherosclerosis (MESA),” Invest Ophthalm. Vis. Sci., vol. 47, no. 6, pp. 2341–2350, 2006.

K. McGeechan, G. Liew, P. Macaskill, L. Irwig, R. Klein, B. E. K. Klein,J. J. Wang, P. Mitchell, J. R. Vingerling, P. T. V. M. Dejong, J. C. M.Witteman,M.M. B. Breteler, J. Shaw, P. Zimmet, and T. Y.Wong, “Metaanalysis:Retinal vessel caliber and risk for coronary heart disease,” Ann.Intern. Med., vol. 151, no. 6, pp. 404–413, 2009.

C. Y.-L. Cheung, Y. Zheng,W. Hsu, M. L. Lee, Q. P. Lau, P. Mitchell, J. J.Wang, R. Klein, and T. Y. Wong, “Retinal vascular tortuosity, blood pressure,and cardiovascular risk factors,” Ophthalmology, vol. 118, pp. 812–818, 2011.

C. Y.-L. Cheung, W. T. Tay, P. Mitchell, J. J. Wang, W. Hsu, M. L. Lee,Q. P. Lau, A. L. Zhu, R. Klein, S. M. Saw, and T. Y. Wong, “Quantitative and qualitative retinal microvascular characteristics and blood pressure,”J. Hypertens, vol. 29, no. 7, pp. 1380–1391, 2011.

Y. Tolias and S. Panas, “A fuzzy vessel tracking algorithm for retinal images based on fuzzy clustering,” IEEE Trans. Med. Imag., vol. 17,no. 2, pp. 263–273, Apr. 1998.

H. Li, W. Hsu, M. L. Lee, and T. Y. Wong, “Automatic grading of retinal vessel caliber,” IEEE Trans. Biomed. Eng., vol. 52, no. 7, pp. 1352–1355,Jul. 2005.

E. Grisan, A. Pesce, A. Giani, M. Foracchia, and A. Ruggeri, “A new tracking system for the robust extraction of retinal vessel structure,” in Proc. IEEE Eng. Med. Biol. Soc., Sep. 2004, vol. 1, pp. 1620–1623.

Y.Yin,M.Adel, M. Guillaume, and S. Bourennane, “Aprobabilistic based method for tracking vessels in retinal images,” in Proc. IEEE Int. Conf.Image Process., Sep. 2010, pp. 4081–4084.

M. Martinez-Perez, A. Highes, A. Stanton, S. Thorn, N. Chapman, A.Bharath, and K. Parker, “Retinal vascular tree morphology: A semiautomatic quantification,” IEEE Trans. Biomed. Eng., vol. 49, no. 8,pp. 912–917, Aug. 2002.

H. Azegrouz and E. Trucco, “Max-min central vein detection in retinal fundus images,” in Proc. IEEE Int. Conf. Image Process., Oct. 2006,pp. 1925–1928.

V. S. Joshi, M. K. Garvin, J. M. Reinhardt, and M. D. Abramoff, “Automated method for the identification and analysis of vascular tree structures in retinal vessel network,” inProc. SPIEConf.Med. Imag., 2011, vol. 7963,no. 1, pp. 1–11.

B. Al-Diri, A. Hunter,D. Steel, andM.Habib, “Automated analysis of retinal vascular network connectivity,” Comput. Med. Imag. Graph., vol. 34,no. 6, pp. 462–470, 2010.

K. Rothaus, X. Jiang, and P. Rhiem, X. Jiang, and P. Rhiem, “Separation of the retinal vascular graph in arteries and veins based upon structural knowledge,” Imag. Vis. Comput., vol. 27, pp. 864–875, 2009.



  • There are currently no refbacks.

Copyright (c) 2015 COMPUSOFT "An International Journal of Advanced Computer Technology"